Hugh S Markus Selected Research

Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)

1/2018	Role of Blood Lipids in the Development of Ischemic Stroke and its Subtypes: A Mendelian Randomization Study.
1/2018	Location, number and factors associated with cerebral microbleeds in an Italian-British cohort of CADASIL patients.
1/2018	Does Treating Vascular Risk Factors Prevent Dementia and Alzheimer's Disease? A Systematic Review and Meta-Analysis.
11/2014	Treatment of vascular risk factors in patients with a diagnosis of Alzheimer's disease: a systematic review.

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Hugh S Markus Research Topics

Disease

92	Stroke (Strokes) 05/2024 - 06/2003
38	Ischemic Stroke 01/2023 - 08/2003
17	Lacunar Stroke 04/2024 - 02/2003
17	Atherosclerosis 12/2023 - 04/2002
15	Inflammation (Inflammations) 04/2024 - 02/2002
15	Cerebral Small Vessel Diseases 04/2024 - 01/2004
15	Carotid Stenosis (Carotid Artery Stenosis) 10/2014 - 03/2002
14	Dementia (Dementias) 01/2023 - 11/2014
10	Pathologic Constriction (Stenosis) 01/2022 - 03/2005
10	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 04/2002
9	Hemorrhage 05/2024 - 08/2010
9	Hypertension (High Blood Pressure) 01/2023 - 11/2007
9	CADASIL 05/2022 - 08/2003
8	Embolic Stroke 01/2019 - 03/2005
7	Cognitive Dysfunction 01/2023 - 04/2008
7	Transient Ischemic Attack 01/2018 - 04/2012
6	Myocardial Infarction 12/2023 - 12/2006
6	Atrial Fibrillation 10/2022 - 06/2002
6	Disease Progression 02/2021 - 05/2004
6	Alzheimer Disease (Alzheimer's Disease) 09/2020 - 04/2008
6	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020 - 05/2004
6	Leukoaraiosis 11/2014 - 02/2003
6	Carotid Artery Diseases 06/2011 - 02/2003
5	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2023 - 11/2014
5	Genetic Predisposition to Disease (Genetic Predisposition) 10/2022 - 02/2016
3	Blood Vessel Dissection 05/2024 - 02/2017
3	Atherosclerotic Plaque (Atheroma) 12/2023 - 05/2013
3	Type 2 Diabetes Mellitus (MODY) 10/2023 - 02/2011
3	Atrophy 01/2022 - 01/2011
3	Insulin Resistance 01/2021 - 05/2004
3	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2021 - 05/2014
3	Thrombosis (Thrombus) 01/2020 - 12/2008
3	Vascular Diseases (Vascular Disease) 10/2018 - 06/2009
3	Genetic Risk Score 10/2017 - 01/2016
3	Intracranial Embolism 03/2015 - 02/2007
2	Thromboembolism 04/2024 - 08/2011
2	COVID-19 10/2021 - 01/2020
2	Brain Ischemia (Cerebral Ischemia) 09/2021 - 03/2015
2	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 01/2021 - 04/2008
2	Neuroinflammatory Diseases 09/2020 - 11/2017
2	Schizophrenia (Dementia Praecox) 01/2017 - 01/2016
2	Infections 02/2016 - 02/2002

Drug/Important Bio-Agent (IBA)

26	Biomarkers (Surrogate Marker)IBA 05/2024 - 08/2003
10	AnticoagulantsIBA 05/2024 - 06/2002
9	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/2024 - 03/2002
9	C-Reactive ProteinIBA 04/2024 - 04/2002
9	danaparoid (Orgaran)FDA Link 01/2019 - 06/2003
7	Fibrinogen (Factor I)FDA Link 01/2022 - 09/2013
7	HomocysteineIBA 01/2019 - 01/2004
7	Clopidogrel (Plavix)FDA Link 01/2017 - 05/2005
6	Proteins (Proteins, Gene)FDA Link 12/2023 - 04/2008
6	LipidsIBA 10/2023 - 01/2018
6	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 01/2015
6	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2019 - 03/2005
5	Amyloid (Amyloid Fibrils)IBA 01/2023 - 11/2017
5	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 09/2006
4	Histone Deacetylases (Histone Deacetylase)IBA 12/2023 - 02/2012
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018 - 11/2014
3	Valproic Acid (Depakote)FDA LinkGeneric 12/2023 - 07/2014
3	CholesterolIBA 12/2023 - 01/2019
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2023 - 03/2016
3	Lipoproteins (Lipoprotein)IBA 01/2023 - 01/2017
3	Blood Proteins (Serum Proteins)IBA 10/2022 - 11/2014
3	Cysteine (L-Cysteine)FDA Link 05/2022 - 01/2019
3	CreatinineIBA 01/2022 - 12/2014
3	Histone Deacetylase InhibitorsIBA 01/2022 - 07/2014
3	Tissue Plasminogen Activator (Alteplase)FDA Link 09/2021 - 02/2006
3	Apolipoproteins E (ApoE)IBA 01/2021 - 09/2004
3	MicroRNAs (MicroRNA)IBA 01/2021 - 02/2013
3	Folic Acid (Vitamin M)FDA LinkGeneric 01/2019 - 11/2008
3	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/2019 - 11/2008
2	Minocycline (Cyclops)FDA LinkGeneric 04/2024 - 09/2022
2	LigandsIBA 03/2024 - 06/2009
2	Fluoxetine (Prozac)FDA LinkGeneric 01/2023 - 01/2020
2	HDL CholesterolIBA 01/2023 - 01/2018
2	Valine (L-Valine)FDA Link 01/2023 - 10/2017
2	lipoprotein-associated coagulation inhibitor (TFPI)IBA 10/2022 - 02/2003
2	Apolipoprotein E4IBA 10/2022 - 01/2021
2	Epidermal Growth Factor (EGF)IBA 05/2022 - 01/2019
2	Notch3 ReceptorIBA 05/2022 - 01/2019
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 02/2003
2	P-2 (P 2)IBA 12/2018 - 12/2012
2	VitaminsIBA 10/2018 - 01/2018
2	25-hydroxyvitamin DIBA 10/2018 - 09/2018
2	Antihypertensive Agents (Antihypertensives)IBA 01/2018 - 08/2010
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2018 - 07/2014
2	LDL CholesterolIBA 01/2018 - 05/2014
2	Insulin (Novolin)FDA Link 01/2018 - 08/2017
2	Dipyridamole (Persantine)FDA LinkGeneric 01/2017 - 10/2015
2	Peptide Hydrolases (Proteases)FDA Link 01/2017 - 12/2008
2	Oxygen (Dioxygen)IBA 02/2016 - 03/2015
2	Collagen Type IV (Type IV Collagen)IBA 12/2015 - 08/2010

Therapy/Procedure

42	Therapeutics 03/2024 - 03/2002
9	Secondary Prevention 04/2024 - 05/2010
8	Thrombectomy 03/2024 - 01/2020
8	Carotid Endarterectomy 04/2014 - 10/2002
4	Endarterectomy (Thromboendarterectomy) 04/2014 - 10/2009
3	Activities of Daily Living (ADL) 01/2023 - 05/2016
3	Stents 08/2019 - 09/2017